Who are we? CNAP is a basic research Center of Excellence established by the Danish National Research Foundation at Aalborg University, Denmark (). We do frontline fundamental research to identify novel mechanisms involved in the dynamics of pain neuroplasticity and advance the understandings of this topic. The mechanisms of pain neuroplasticity may include neuronal reorganisation, increased/decreased gain of signal transduction or transmission, altered neuronal receptor functions, or changes across the pain system. CNAP applies a basic research approach to study novel aspects of the human pain neuroplasticity, using an interdisciplinary and translational neuro-engineering and neuroscience approach. We believe that this approach, including provoking, probing, and modulation of the dynamic neuroplastic properties of the pain system over time will foster new fundamental discoveries and change the state of the art.